Rabeprazole sodium and domperidone capsules are a combination medication used to treat various gastrointestinal conditions. Let's delve into the detailed pharmacology and uses of each component:
1. Rabeprazole Sodium: - Pharmacology: - Rabeprazole is a proton pump inhibitor (PPI). It works by inhibiting the action of the proton pump in the gastric parietal cells. This pump is responsible for the final step in the secretion of gastric acid, making it a potent suppressor of gastric acid production. Rabeprazole selectively and irreversibly inhibits the hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cell. This inhibition leads to a decrease in both basal and stimulated gastric acid secretion. - Uses: - Gastroesophageal Reflux Disease (GERD): Rabeprazole is used to treat GERD, a condition where stomach acid flows back into the esophagus, causing symptoms such as heartburn and regurgitation. - Pept…
1. Rabeprazole Sodium:
- Pharmacology:
- Rabeprazole is a proton pump inhibitor (PPI). It works by inhibiting the action of the proton pump in the gastric parietal cells. This pump is responsible for the final step in the secretion of gastric acid, making it a potent suppressor of gastric acid production. Rabeprazole selectively and irreversibly inhibits the hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cell. This inhibition leads to a decrease in both basal and stimulated gastric acid secretion.
- Uses:
- Gastroesophageal Reflux Disease (GERD): Rabeprazole is used to treat GERD, a condition where stomach acid flows back into the esophagus, causing symptoms such as heartburn and regurgitation.
- Pept…